CiC-PD

Understanding medication adherence and its effect on motor function in people with Parkinson's

Principal investigator: Dr Silvia Del Din

BAM Co-applicants: Prof Lynn Rochester, Dr Lisa Alcock, Prof Alison Yarnall

Project members: Emma Packer

Background

Three circles linked to a stick figure. A cross represents medical symptoms; a timer represents wearing off; and lightning symbols represent pain and rigidity. The middle figure with entangled arrows on the chest represents symptom fluctuation.
Graphic of four pills representing the complexity of Parkinson's medication regimens 
With time symptom fluctuations appear making monitoring of people with PD increasingly challenging
Parkinson’s disease (PD) requires complex medication regimens to alleviate motor symptoms
A stick figure with tremor is wearing a digital sensor monitoring motor symptoms. 
Digital health technology allows remote monitoring of people with PD’s and could be used to better understand their daily symptoms

Methods

An infographic representing the integrated methods used in this study. A smartphone, a smartwatch and an activity monitor are integrated into a digital system monitoring medication intakes, mobility and motor symptoms in Parkinson's disease. 
This cross-sectional, mixed-methods study uses digital health technology to better understand medication adherence affects motor symptoms and mobility

Overarching aim

A fluctuating line, a cross representing medical symptoms and tablets are drawn around a magnifying glass that looks at a stick figure. This represents the aim of this study that is to personalise treatments for Parkinson’s to improve quality of life 
This study aims at modelling changes in PD symptoms with medication intake and thereby optimise medication prescription

Funder: MRC + EPSRC/NIHR

Contact: Dr Silvia Del Din